专任教师-刘敏卓简介

发布时间:2023-07-19 

【基本信息】

说明: 刘敏卓-照片-1

姓名

刘敏卓

职称

讲师

学位

博士

邮箱

120691761@qq.com

【教育经历】

2004.09-2008.06 湖南中医药大学中药学 学士

2008.09-2011.06 中国药科大学天然药物化学硕士

2015.09-2019.12 中南大学分析化学博士

【科研项目】

1.湖南省自然科学基金面上项目,2023JJ30090,栀子抗氧化应激与炎症反应防治干性AMD活性成分的高效发现及作用机制研究,2023/01-2025/12,在研,主持

2.湖南省重点研发计划项目子课题,2022WK2008,栀子藏红花素类成分的定向制备分离技术及其在AMD中的功效与机制研究,2022/01-2023/12,在研,主持

3.长沙学院人才引进科研基金项目,SF2144,栀子中治疗干性老年黄斑变性活性成分研究,2020/09-2025/08,在研,主持

【著作论文】

1. Jie Zhang#, Minzhuo Liu#, Meixia Xu, Zhiguo Chen, Xucong Peng, Qiusheng Yang, Ting Cai, Zhihong Zeng*. Discovery of a new polymorph of clotrimazole through melt crystallization: Understanding nucleation and growth kinetics. J. Chem. Phys. 2023, 158: 034503.

2. Jie Zhang,* Meixia Xu, Shuiqing Wu, Zhiguo Chen, Liquan Luo, Taotao Zi, Xucong Peng, Qiusheng Yang,Minzhuo Liu,* Zhihong Zeng*. Investigation into Surface Effects on the Crystal Nucleation and Growth of Clotrimazole Polymorphs. Cryst. Growth Des. 2023, 23, 3535-3543.

3. Zhang J#,Liu M#, Zeng Z*.The antisolvent coprecipitation method for enhanced bioavailability of poorly water-soluble drugs. Int J Pharm. 2022, 626: 122043.

4. Minzhuo Liu, Xujie Li, Qi Liu*, Siqi Xie, Miao Chen, Lumin Wang, Yinghui Feng, Xiaoqing Chen*. Comprehensive profiling ofα-glucosidase inhibitors from the leaves of Rubus suavissimus using an off-line hyphenation of HSCCC, ultrafiltration HPLC-UV-MS and prep-HPLC, Journal of Food Composition and Analysis, 2020, 85: 103336.

5. Minzhuo Liu, Xujie Li, Qi Liu*, Fawei Zhu, Miao Chen, Xiaoqing Chen*. Preparative isolation and purification of twelve main antioxidants from the roots of Polygonum multiflorum Thunb using HSCCC and preparative HPLC guided by DPPH-HPLC. Journal of Separation Science, 2020, 43: 1415-1422.

6.Minzhuo Liu, Fen Tang, Qi Liu*, Jianbo Xiao, Xiaoqing Chen*. Inhibition of resveratrol glucosides (REs) on advanced glycation endproducts (AGEs) formation: inhibitory mechanism and structure-activity relationship, Natural Product Research, 2020, 34(17): 2490-2494.

7. Minzhuo Liu, Qi Liu*, Miao Chen, Xueqian Huang, Xiaoqing Chen*. Large-scale separation of acetylcholinesterase inhibitors from Zanthoxylum nitidum by pH-zone-refining counter-current chromatography target-guided by ultrafiltration HPLC-MS screening, Journal of Separation Science, 2019, 42: 1194-1201.

8. Minzhuo Liu, Xueqian Huang, Qi Liu*, Xiaoqing Chen*. Target-guided separation ofα-glucosidase inhibitors from Potentilla kleiniana Wight et Arn via gradient elution HSCCC coupled with ultrafiltration HPLC-MS screening, Phytochemical Analysis, 2019, 30: 661-668.

9. Minzhuo Liu, Xueqian Huang, Qi Liu*, Shuyun Shi, Xiaoqing Chen*. Rapid screening and identification of antioxidants in the leaves of Malus hupehensis using off-line two-dimensional HPLC-UV-MS/MS coupled with a 1,1’-diphenyl-2-picrylhydrazyl assay, Journal of Separation Science, 2018, 41: 2536-2543.

10.刘敏卓,张小月,张灵芝,曹孟君,叶素芳,吴泽华,张杰*,曾志红*.竹茹总黄酮超声波处理与纤维素酶协同提取工艺优化及其体外抗氧化活性分析.食品工业科技,2023,https://doi.org/10.13386/j.issn1002-0306.2022120009.

11.刘敏卓,张思佳,杨春华,夏烨,刘静涵,梁敬钰*.生附子中C19型二萜生物碱的高速逆流色谱分离及其结构鉴定.色谱,2011, 29: 430-434.

【重要奖项】

1.获2022年度长沙学院“优秀教研室主任”

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